Frequently individuals who are ill take supplements and get iller and iller

Supplements taken in high dosages can result in genetic loci becoming hypermethylated in gastrointestinal tracts and/or livers turning off transcription of various genes connected to enzymes whose activities are increased by such supplements. At some point individuals could state 'These supplements are not helping a bit. I am going to stop taking supplements.'

Individuals who are ill and take more and more supplements can get iller and iller and and what is even worse land up in holes that are very difficult to climb out of even where supplements are stopped. Individuals who stop taking high dosages of supplements do not automatically get better as genetic loci are hypermethylated in gastrointestinal tracts and/or livers and transcription of genes is turned off. There are steps that can be taken. See this post on backing out of an antioxidant laden diets.

Why do individuals start taking supplements? Individuals feel unwell to very unwell due having diets containing dietary antioxidants.